- Schuylkill Medical Center
- Schuylkill Medical Center South
- Schuylkill United Way
- Schwenckfeld Manor Apartments
- Select Specialty Hospital, Erie
- Select Specialty Hospital, Greensburg
- Select Specialty Hospital, Pittsburgh
- SelecTrim Corporation
- Seton Hill Child Services Inc.
- Sharon Regional Medical Center
- Shepherd Wellness Center
- Sheraton Bucks County Hotel, Langhome
- Sheraton Frazer Great Valley Hotel
- Sherwood Oaks
- Shippensburg University
- Sky Insurance
- Slovenian Savings and Loan Assoc., Franklin-Conemaugh
- SMS Demag, Inc.
- Snavely Forest Products Inc.
- SNC Lavalaw
- Snow Ball Foods, LLC
- Society for Protective Coatings
- Software Management, Inc.
- Solutions for Progress
- Somerset Hospital
- Souderton Mennonite Homes
- South Winds, Inc.
- Southeast Asian Mutual Assistance Association Coalition
- Southwestern Pennsylvania Human Services Inc.
- Southwesterns Pennsylvania Corp.
- Spang and Company
- Spectrim
- Spectrum Health Services
- Spring House Estates
- Spring Mill Presbyterian Village
- Springfield Hospital
- St. Christopher's Hospital for Children
- St. Clair Hospital
- St. Luke's Carbon
- St. Luke's Hospital - Allentown Campus
- St. Luke's Hospital - Anderson Campus
- St. Luke's Hospital - Gnaden Huetten Campus
- St. Luke's Hospital - Miners Campus
- St. Luke's Hospital - Monroe Campus
- St. Luke's Hospital - Quakertown Campus
- St. Luke's Hospital - Sacred Heart Campus
- St. Luke's Lehighton Campus
- St. Luke's University Hospital - Bethlehem
- St. Mary Medical Center
- St. Mary's Health Center